Molecular Analysis of Vector Genome Structures After Liver Transduction by Conventional and Self-Complementary Adeno-Associated Viral Serotype Vectors in Murine and Nonhuman Primate Models

Vectors based on several new adeno-associated viral (AAV) serotypes demonstrated strong hepatocyte tropism and transduction efficiency in both small- and large-animal models for liver-directed gene transfer. Efficiency of liver transduction by AAV vectors can be further improved in both murine and n...

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Autores principales: Sun, Xun, Lu, You, Bish, Lawrence T., Calcedo, Roberto, Wilson, James M., Gao, Guangping
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2010
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938357/
https://ncbi.nlm.nih.gov/pubmed/20113166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.214
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