Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates

Widespread distribution of gene products at clinically relevant levels throughout the CNS has been challenging. Adeno-associated virus type 9 (AAV9) vector has been reported as a good candidate for intravascular gene delivery, but low levels of preexisting antibody titers against AAV in the blood ab...

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Main Authors: Samaranch, Lluis, Salegio, Ernesto A., San Sebastian, Waldy, Kells, Adrian P., Foust, Kevin D., Bringas, John R., Lamarre, Clementine, Forsayeth, John, Kaspar, Brian K., Bankiewicz, Krystof S.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327605/
https://ncbi.nlm.nih.gov/pubmed/22201473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.200
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