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Axonal transport of adeno-associated viral vectors is serotype-dependent
We have previously shown that AAV2 undergoes anterograde axonal transport in rat and non-human primate brain. We screened other AAV serotypes for axonal transport and found that AAV6 is transported almost exclusively in a retrograde direction and, like AAV2, it is also neuron-specific in rat brain....
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3381869/ https://ncbi.nlm.nih.gov/pubmed/22418061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.27 |
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