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High-Level Transgene Expression in Nonhuman Primate Liver with Novel Adeno-Associated Virus Serotypes Containing Self-Complementary Genomes

Adeno-associated virus (AAV) vectors are being considered for in vivo applications of gene therapy in the treatment of a variety of disorders. This study evaluates the biology of second-generation vectors based on the novel serotypes AAV7 and AAV8 and containing self-complementary genomes in the non...

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Detalhes bibliográficos
Main Authors: Gao, Guang-Ping, Lu, You, Sun, Xun, Johnston, Julie, Calcedo, Roberto, Grant, Rebecca, Wilson, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472562/
https://ncbi.nlm.nih.gov/pubmed/16731960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00526-06
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