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Ex Vivo Serotype-Specific Transduction of Equine Joint Tissue by Self-Complementary Adeno-Associated Viral Vectors

Cell transplantation for the treatment of joint disease is an important clinical tool. Genetic modification of cells before transplantation has shown enhanced healing. Ex vivo genetic modification of joint tissue cells with various adeno-associated virus (AAV) serotypes has not been investigated. Th...

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Autori principali: Goodrich, L.R., Choi, V.W., Carbone, B.A. Duda, McIlwraith, C.W., Samulski, R.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861962/
https://ncbi.nlm.nih.gov/pubmed/19642864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.030
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