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Adeno-Associated Viral Vectors Show Serotype Specific Transduction of Equine Joint Tissue Explants and Cultured Monolayers

Adeno-associated virus (AAV) receptors range from heparan sulfate proteoglycan to sialic acid moieties present on cell surfaces. Abundance of the glycan profiles is greatly influenced by animal species, cell type, and culture conditions. The objective of this study was to determine whether AAV serot...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Hemphill, Daniel D., McIlwraith, C. Wayne, Samulski, R. Jude, Goodrich, Laurie R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894424/
https://ncbi.nlm.nih.gov/pubmed/25069854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05861
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