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Evaluation of Adeno-Associated Viral Vectors for Liver-Directed Gene Transfer in Dogs

This study evaluated six adeno-associated viral (AAV) vectors expressing green fluorescent protein (GFP) from the liver-specific thyroid hormone–binding globulin (TBG) promoter made with novel capsids in canine liver-directed gene transfer. Studies in 1.5-month-old dogs, which were administered vect...

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Main Authors: Bell, Peter, Gao, Guangping, Haskins, Mark E., Wang, Lili, Sleeper, Meg, Wang, Huan, Calcedo, Roberto, Vandenberghe, Luk H., Chen, Shu-Jen, Weisse, Chick, Withnall, Elanor, Wilson, James M.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159528/
https://ncbi.nlm.nih.gov/pubmed/21204705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.194
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