Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale

Adeno-associated viral (AAV) manufacturing at scale continues to hinder the application of AAV technology to gene therapy studies. Although scalable systems based on AAV–adenovirus, AAV–herpesvirus, and AAV–baculovirus hybrids hold promise for clinical applications, they require time-consuming gener...

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Bibliographic Details
Main Authors: Lock, Martin, Alvira, Mauricio, Vandenberghe, Luk H., Samanta, Arabinda, Toelen, Jaan, Debyser, Zeger, Wilson, James M.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957274/
https://ncbi.nlm.nih.gov/pubmed/20497038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.055
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