Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale

Adeno-associated viral (AAV) manufacturing at scale continues to hinder the application of AAV technology to gene therapy studies. Although scalable systems based on AAV–adenovirus, AAV–herpesvirus, and AAV–baculovirus hybrids hold promise for clinical applications, they require time-consuming gener...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lock, Martin, Alvira, Mauricio, Vandenberghe, Luk H., Samanta, Arabinda, Toelen, Jaan, Debyser, Zeger, Wilson, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2010
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957274/
https://ncbi.nlm.nih.gov/pubmed/20497038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.055
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