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Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale

Adeno-associated viral (AAV) manufacturing at scale continues to hinder the application of AAV technology to gene therapy studies. Although scalable systems based on AAV–adenovirus, AAV–herpesvirus, and AAV–baculovirus hybrids hold promise for clinical applications, they require time-consuming gener...

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Autores principales: Lock, Martin, Alvira, Mauricio, Vandenberghe, Luk H., Samanta, Arabinda, Toelen, Jaan, Debyser, Zeger, Wilson, James M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957274/
https://ncbi.nlm.nih.gov/pubmed/20497038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.055
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