Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale

Adeno-associated viral (AAV) manufacturing at scale continues to hinder the application of AAV technology to gene therapy studies. Although scalable systems based on AAV–adenovirus, AAV–herpesvirus, and AAV–baculovirus hybrids hold promise for clinical applications, they require time-consuming gener...

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Bibliografiske detaljer
Main Authors: Lock, Martin, Alvira, Mauricio, Vandenberghe, Luk H., Samanta, Arabinda, Toelen, Jaan, Debyser, Zeger, Wilson, James M.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2010
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957274/
https://ncbi.nlm.nih.gov/pubmed/20497038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.055
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