Hepatic Gene Transfer in Neonatal Mice by Adeno-Associated Virus Serotype 8 Vector

For genetic diseases that manifest at a young age with irreversible consequences, early treatment is critical and essential. Neonatal gene therapy has the advantages of achieving therapeutic effects before disease manifestation, a low vector requirement and high vector-to-cell ratio, and a relativel...

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Bibliographic Details
Main Authors: Wang, Lili, Wang, Huan, Bell, Peter, McMenamin, Deirdre, Wilson, James M.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2012
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360497/
https://ncbi.nlm.nih.gov/pubmed/22098408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.183
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