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Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats

BACKGROUND: We have previously shown that essential hypertension in humans and spontaneously hypertensive rats (SHR), is associated with increased levels of ceramide and marked alterations in sphingolipid biology. Pharmacological elevation of ceramide in isolated carotid arteries of SHR leads to vas...

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Bibliografiset tiedot
Päätekijät: Spijkers, Léon J. A., Janssen, Ben J. A., Nelissen, Jelly, Meens, Merlijn J. P. M. T., Wijesinghe, Dayanjan, Chalfant, Charles E., De Mey, Jo G. R., Alewijnse, Astrid E., Peters, Stephan L. M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240660/
https://ncbi.nlm.nih.gov/pubmed/22195025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029222
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