Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats

BACKGROUND: We have previously shown that essential hypertension in humans and spontaneously hypertensive rats (SHR), is associated with increased levels of ceramide and marked alterations in sphingolipid biology. Pharmacological elevation of ceramide in isolated carotid arteries of SHR leads to vas...

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Detaylı Bibliyografya
Asıl Yazarlar: Spijkers, Léon J. A., Janssen, Ben J. A., Nelissen, Jelly, Meens, Merlijn J. P. M. T., Wijesinghe, Dayanjan, Chalfant, Charles E., De Mey, Jo G. R., Alewijnse, Astrid E., Peters, Stephan L. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240660/
https://ncbi.nlm.nih.gov/pubmed/22195025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029222
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