Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats

BACKGROUND: We have previously shown that essential hypertension in humans and spontaneously hypertensive rats (SHR), is associated with increased levels of ceramide and marked alterations in sphingolipid biology. Pharmacological elevation of ceramide in isolated carotid arteries of SHR leads to vas...

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書誌詳細
主要な著者: Spijkers, Léon J. A., Janssen, Ben J. A., Nelissen, Jelly, Meens, Merlijn J. P. M. T., Wijesinghe, Dayanjan, Chalfant, Charles E., De Mey, Jo G. R., Alewijnse, Astrid E., Peters, Stephan L. M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240660/
https://ncbi.nlm.nih.gov/pubmed/22195025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029222
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