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Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats

OBJECTIVE: Long-chain n-3 polyunsaturated fatty acids from oily fish reduce blood pressure (BP) in hypertension. Previously, we demonstrated that hypertension is associated with marked alterations in sphingolipid biology and elevated ceramide-induced vasoconstriction. Here we investigated in spontan...

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Detalhes bibliográficos
Publicado no:J Hypertens
Main Authors: van den Elsen, Lieke W.J., Spijkers, Léon J.A., van den Akker, Rob F.P., van Winssen, Aggie M.H., Balvers, Martin, Wijesinghe, Dayanjan S., Chalfant, Charles E., Garssen, Johan, Willemsen, Linette E.M., Alewijnse, Astrid E., Peters, Stephan L.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312004/
https://ncbi.nlm.nih.gov/pubmed/24569415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000000131
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