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Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide

BACKGROUND: Hypertension is, amongst others, characterized by endothelial dysfunction and vascular remodeling. As sphingolipids have been implicated in both the regulation of vascular contractility and growth, we investigated whether sphingolipid biology is altered in hypertension and whether this i...

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Bibliografiske detaljer
Main Authors: Spijkers, Léon J. A., van den Akker, Rob F. P., Janssen, Ben J. A., Debets, Jacques J., De Mey, Jo G. R., Stroes, Erik S. G., van den Born, Bert-Jan H., Wijesinghe, Dayanjan S., Chalfant, Charles E., MacAleese, Luke, Eijkel, Gert B., Heeren, Ron M. A., Alewijnse, Astrid E., Peters, Stephan L. M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139577/
https://ncbi.nlm.nih.gov/pubmed/21818267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021817
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