Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinase

Multiple reports have demonstrated a role for ceramide kinase (CERK) in the production of eicosanoids. To examine the effects of the genetic ablation of CERK on eicosanoid synthesis, primary mouse embryonic fibroblasts (MEFs) and macrophages were isolated from CERK(−/−) and CERK(+/+) mice, and the c...

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Main Authors: Mietla, Jennifer A., Wijesinghe, Dayanjan S., Hoeferlin, L. Alexis, Shultz, Michael D., Natarajan, Ramesh, Fowler, Alpha A., Chalfant, Charles E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Biochemistry and Molecular Biology 2013
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679386/
https://ncbi.nlm.nih.gov/pubmed/23576683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035683
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