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Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinase

Multiple reports have demonstrated a role for ceramide kinase (CERK) in the production of eicosanoids. To examine the effects of the genetic ablation of CERK on eicosanoid synthesis, primary mouse embryonic fibroblasts (MEFs) and macrophages were isolated from CERK(−/−) and CERK(+/+) mice, and the c...

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Autors principals: Mietla, Jennifer A., Wijesinghe, Dayanjan S., Hoeferlin, L. Alexis, Shultz, Michael D., Natarajan, Ramesh, Fowler, Alpha A., Chalfant, Charles E.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679386/
https://ncbi.nlm.nih.gov/pubmed/23576683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035683
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