Nonvesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

Phosphorylated sphingolipids [ceramide-1-phosphate (C1P) and sphingosine-1-phosphate (S1P)] have emerged as key regulators of cell growth, survival, migration, and inflammation(1–5). C1P (Fig. 1a) produced by ceramide kinase is an activator of group IVA cytosolic phospholipase A(2)α (cPLA(2)α), the...

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Detalhes bibliográficos
Main Authors: Simanshu, Dhirendra K., Kamlekar, Ravi Kanth, Wijesinghe, Dayanjan S., Zou, Xianqiong, Zhai, Xiuhong, Mishra, Shrawan K., Molotkovsky, Julian G., Malinina, Lucy, Hinchcliffe, Edward H., Chalfant, Charles E., Brown, Rhoderick E., Patel, Dinshaw J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951269/
https://ncbi.nlm.nih.gov/pubmed/23863933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12332
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