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Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer’s disease

The largest genetic risk for late-onset Alzheimer’s disease (AD) resides at the apolipoprotein E gene (APOE) locus, which has three common alleles (ε2, ε3, ε4) that encode three isoforms (apoE2, apoE3, apoE4). The very strong association of the APOE ε4 allele with AD risk and its role in the accumul...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Keene, C. Dirk, Cudaback, Eiron, Li, Xianwu, Montine, Kathleen S., Montine, Thomas J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237894/
https://ncbi.nlm.nih.gov/pubmed/21907569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2011.08.002
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