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Apolipoprotein C-I is an APOE genotype-dependent suppressor of glial activation
BACKGROUND: Inheritance of the human ϵ4 allele of the apolipoprotein (apo) E gene (APOE) significantly increases the risk of developing Alzheimer’s disease (AD), in addition to adversely influencing clinical outcomes of other neurologic diseases. While apoE isoforms differentially interact with amyl...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3490924/ https://ncbi.nlm.nih.gov/pubmed/22883744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-192 |
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