Apolipoprotein C-I is an APOE genotype-dependent suppressor of glial activation

BACKGROUND: Inheritance of the human ϵ4 allele of the apolipoprotein (apo) E gene (APOE) significantly increases the risk of developing Alzheimer’s disease (AD), in addition to adversely influencing clinical outcomes of other neurologic diseases. While apoE isoforms differentially interact with amyl...

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Détails bibliographiques
Auteurs principaux: Cudaback, Eiron, Li, Xianwu, Yang, Yue, Yoo, Thomas, Montine, Kathleen S, Craft, Suzanne, Montine, Thomas J, Keene, Christopher Dirk
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490924/
https://ncbi.nlm.nih.gov/pubmed/22883744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-192
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