Apolipoprotein E isoform-dependent microglia migration

Complement component C5a and ATP are potent effectors of microglial movement and are increased in diverse neurodegenerative diseases and at sites of injury. Apolipoprotein E (apoE) influences microglial function, and different human apoE isoforms confer variable risk for development of neurodegenera...

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Autores principales: Cudaback, Eiron, Li, Xianwu, Montine, Kathleen S., Montine, Thomas J., Keene, C. Dirk
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2011
Materias:
Research Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101033/
https://ncbi.nlm.nih.gov/pubmed/21385991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-176891
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