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Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice
BACKGROUND: Inheritance of the three different alleles of the human apolipoprotein (apo) E gene (APOE) are associated with varying risk or clinical outcome from a variety of neurologic diseases. ApoE isoform-specific modulation of several pathogenic processes, in addition to amyloid β metabolism in...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502133/ https://ncbi.nlm.nih.gov/pubmed/16603079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-3-10 |
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