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Functional imaging of proteases: recent advances in the design and application of substrate- and activity- based probes

Proteases are enzymes that cleave peptide bonds in protein substrates. This process can be important for regulated turnover of a target protein but it can also produce protein fragments that then perform other functions. Because the last few decades of protease research have confirmed that proteolys...

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Dettagli Bibliografici
Autori principali: Edgington, Laura E., Verdoes, Martijn, Bogyo, Matthew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237724/
https://ncbi.nlm.nih.gov/pubmed/22098719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2011.10.012
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