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Evolution of coordinated mutagenesis and somatic hypermutation in VH5
The VH5 human antibody gene was analyzed using a computer program (mfg) which simulates transcription, to better understand transcription-driven mutagenesis events that occur during “phase 1” of somatic hypermutation. Results show that the great majority of mutations in the non-transcribed strand oc...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235918/ https://ncbi.nlm.nih.gov/pubmed/22056943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.10.001 |
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