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Kinetic models reveal the in vivo mechanisms of mutagenesis in microbes and man

This review summarizes the evidence indicating that mutagenic mechanisms in vivo are essentially the same in all living cells. Unique metabolic reactions to a particular environmental stress apparently target specific genes for increased rates of transcription and mutation, resulting in higher mutat...

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Détails bibliographiques
Auteurs principaux: Wright, Barbara E., Schmidt, Karen H., Minnick, Michael F.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631585/
https://ncbi.nlm.nih.gov/pubmed/23274173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2012.12.003
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