Structural Polymorphism in Amyloids: NEW INSIGHTS FROM STUDIES WITH Y145Stop PRION PROTEIN FIBRILS

The C-terminally-truncated human prion protein variant Y145Stop (or PrP23–144), associated with a familial prion disease, provides a valuable model for studying the fundamental properties of protein amyloids. In previous solid-state NMR experiments, we established that the β-sheet core of the PrP23–...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jones, Eric M., Wu, Bo, Surewicz, Krystyna, Nadaud, Philippe S., Helmus, Jonathan J., Chen, Shugui, Jaroniec, Christopher P., Surewicz, Witold K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234922/
https://ncbi.nlm.nih.gov/pubmed/22002245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302539
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares