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Species-dependent structural polymorphism of Y145Stop prion protein amyloid revealed by solid-state NMR spectroscopy

One of the most puzzling aspects of the prion diseases is the intricate relationship between prion strains and interspecies transmissibility barriers. Previously we have shown that certain fundamental aspects of mammalian prion propagation, including the strain phenomenon and species barriers, can b...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Theint, Theint, Nadaud, Philippe S., Aucoin, Darryl, Helmus, Jonathan J., Pondaven, Simon P., Surewicz, Krystyna, Surewicz, Witold K., Jaroniec, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622040/
https://ncbi.nlm.nih.gov/pubmed/28963458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00794-z
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