Species-dependent structural polymorphism of Y145Stop prion protein amyloid revealed by solid-state NMR spectroscopy

One of the most puzzling aspects of the prion diseases is the intricate relationship between prion strains and interspecies transmissibility barriers. Previously we have shown that certain fundamental aspects of mammalian prion propagation, including the strain phenomenon and species barriers, can b...

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Publicado en:Nat Commun
Main Authors: Theint, Theint, Nadaud, Philippe S., Aucoin, Darryl, Helmus, Jonathan J., Pondaven, Simon P., Surewicz, Krystyna, Surewicz, Witold K., Jaroniec, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622040/
https://ncbi.nlm.nih.gov/pubmed/28963458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00794-z
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