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Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction
Understanding platelet biology has been aided by studies of mice with mutations in key megakaryocytic transcription factors. We have shown that point mutations in the GATA1 cofactor FOG1 that disrupt binding to the nucleosome remodeling and deacetylase (NuRD) complex have erythroid and megakaryocyte...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234671/ https://ncbi.nlm.nih.gov/pubmed/21989988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-363580 |
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