Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction

Understanding platelet biology has been aided by studies of mice with mutations in key megakaryocytic transcription factors. We have shown that point mutations in the GATA1 cofactor FOG1 that disrupt binding to the nucleosome remodeling and deacetylase (NuRD) complex have erythroid and megakaryocyte...

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Hlavní autoři: Wang, Yuhuan, Meng, Ronghua, Hayes, Vincent, Fuentes, Rudy, Yu, Xiang, Abrams, Charles S., Heijnen, Harry F. G., Blobel, Gerd A., Marks, Michael S., Poncz, Mortimer
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Platelets and Thrombopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234671/
https://ncbi.nlm.nih.gov/pubmed/21989988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-363580
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