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FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1

Transcription factor GATA-1 and its cofactor FOG-1 coordinate erythroid cell maturation by activating erythroid-specific genes and repressing genes associated with the undifferentiated state. Here we show that FOG-1 binds to the NuRD corepressor complex in vitro and in vivo. The interaction is media...

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Hlavní autoři: Hong, Wei, Nakazawa, Minako, Chen, Ying-Yu, Kori, Rajashree, Vakoc, Christopher R, Rakowski, Carrie, Blobel, Gerd A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1173144/
https://ncbi.nlm.nih.gov/pubmed/15920470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600703
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