NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development

GATA transcription factors interact with FOG proteins to regulate tissue development by activating and repressing transcription. FOG-1 (ZFPM1), a co-factor for the haematopoietic factor GATA-1, binds to the NuRD co-repressor complex through a conserved N-terminal motif. Surprisingly, we detected NuR...

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Main Authors: Miccio, Annarita, Wang, Yuhuan, Hong, Wei, Gregory, Gregory D, Wang, Hongxin, Yu, Xiang, Choi, John K, Shelat, Suresh, Tong, Wei, Poncz, Mortimer, Blobel, Gerd A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824460/
https://ncbi.nlm.nih.gov/pubmed/19927129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.336
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