FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment

Nuclear factors regulate the development of complex tissues by promoting the formation of one cell lineage over another. The cofactor FOG1 interacts with transcription factors GATA1 and GATA2 to control erythroid and megakaryocyte (MK) differentiation. In contrast, FOG1 antagonizes the ability of GA...

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Detalhes bibliográficos
Main Authors: Gregory, Gregory D., Miccio, Annarita, Bersenev, Alexey, Wang, Yuhuan, Hong, Wei, Zhang, Zhe, Poncz, Mortimer, Tong, Wei, Blobel, Gerd A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844012/
https://ncbi.nlm.nih.gov/pubmed/20065294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-251280
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