FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment

Nuclear factors regulate the development of complex tissues by promoting the formation of one cell lineage over another. The cofactor FOG1 interacts with transcription factors GATA1 and GATA2 to control erythroid and megakaryocyte (MK) differentiation. In contrast, FOG1 antagonizes the ability of GA...

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Autori principali: Gregory, Gregory D., Miccio, Annarita, Bersenev, Alexey, Wang, Yuhuan, Hong, Wei, Zhang, Zhe, Poncz, Mortimer, Tong, Wei, Blobel, Gerd A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844012/
https://ncbi.nlm.nih.gov/pubmed/20065294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-251280
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