FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment

Nuclear factors regulate the development of complex tissues by promoting the formation of one cell lineage over another. The cofactor FOG1 interacts with transcription factors GATA1 and GATA2 to control erythroid and megakaryocyte (MK) differentiation. In contrast, FOG1 antagonizes the ability of GA...

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Bibliografiske detaljer
Main Authors: Gregory, Gregory D., Miccio, Annarita, Bersenev, Alexey, Wang, Yuhuan, Hong, Wei, Zhang, Zhe, Poncz, Mortimer, Tong, Wei, Blobel, Gerd A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844012/
https://ncbi.nlm.nih.gov/pubmed/20065294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-251280
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