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The Zinc Finger and C-terminal Domains of MTA Proteins are Required for FOG-2 Mediated Transcriptional Repression via the NuRD Complex

FOG-2 is a transcriptional co-regulator that is required for cardiac morphogenesis as mice deficient in this factor die during mid-gestation of cardiac malformations. FOG-2 interacts with GATA4 to attenuate GATA4-dependent gene expression. The first 12 amino acids of FOG-2 (the FOG Repression Motif)...

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Detalhes bibliográficos
Main Authors: Roche, Andrea E., Bassett, Brett J., Samant, Sadhana A., Hong, Wei, Blobel, Gerd A., Svensson, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277079/
https://ncbi.nlm.nih.gov/pubmed/18067919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.10.023
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