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The Zinc Finger and C-terminal Domains of MTA Proteins are Required for FOG-2 Mediated Transcriptional Repression via the NuRD Complex
FOG-2 is a transcriptional co-regulator that is required for cardiac morphogenesis as mice deficient in this factor die during mid-gestation of cardiac malformations. FOG-2 interacts with GATA4 to attenuate GATA4-dependent gene expression. The first 12 amino acids of FOG-2 (the FOG Repression Motif)...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2277079/ https://ncbi.nlm.nih.gov/pubmed/18067919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.10.023 |
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