Tetrazine-trans-Cyclooctene Ligation for the Rapid Construction of (18)F Labeled Probes

A radiolabeling method for bioconjugation based on the Diels-Alder reaction between 3,6-diaryl-s-tetrazines and an (18)F-labeled trans-cyclooctene is described. The reaction proceeds with exceptionally fast rates, making it an effective conjugation method within seconds at low micromolar concentrati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Zibo, Cai, Hancheng, Hassink, Matthew, Blackman, Melissa L., Brown, Richard C. D., Conti, Peter S., Fox, Joseph M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230320/
https://ncbi.nlm.nih.gov/pubmed/20862423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc03078c
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg