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Tetrazine-trans-Cyclooctene Ligation for the Rapid Construction of (18)F Labeled Probes
A radiolabeling method for bioconjugation based on the Diels-Alder reaction between 3,6-diaryl-s-tetrazines and an (18)F-labeled trans-cyclooctene is described. The reaction proceeds with exceptionally fast rates, making it an effective conjugation method within seconds at low micromolar concentrati...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230320/ https://ncbi.nlm.nih.gov/pubmed/20862423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc03078c |
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