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Efficient (18)F labeling of cysteine containing peptides and proteins using the tetrazine-trans-cyclooctene ligation
(18)F PET has a number of attributes that make it clinically attractive, including nearly 100% positron efficiency, very high specific radioactivity, and short half-life of ~110 min. However, the short half-life of (18)F and the poor nucleophilicity of fluoride introduce challenges for the incorpora...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027965/ https://ncbi.nlm.nih.gov/pubmed/23415400 |
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