Tetrazine-tans-cyclooctene ligation for the rapid construction of integrin α(v)β(3) targeted PET tracer based on a cyclic RGD peptide

Labeling biomolecules with (18)F is usually done through coupling with prosthetic groups, which generally requires several time-consuming radiosynthetic steps resulting in low labeling yield. Recently, the tetrazine-trans-cyclooctene ligation has been introduced as a method of bioconjugation that pr...

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Hlavní autoři: Selvaraj, Ramajeyam, Liu, Shuanglong, Hassink, Matthew, Huang, Chiun-wei, Yap, Li-peng, Park, Ryan, Fox, Joseph M., Li, Zibo, Conti, Peter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230322/
https://ncbi.nlm.nih.gov/pubmed/21601452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.04.116
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