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trans-Cyclooctene — a stable, voracious dienophile for bioorthogonal labeling
Discussed herein is the development and advancement of trans-cyclooctene as a tool for facilitating bioorthogonal labeling through reactions with s-tetrazines. While a number of strained alkenes have been shown to combine with tetrazines for applications in bioorthogonal labeling, trans-cyclooctene...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925366/ https://ncbi.nlm.nih.gov/pubmed/23978373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2013.07.031 |
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