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Drug Discovery Toward Antagonists of Methyl-Lysine Binding Proteins

The recognition of methyl-lysine and -arginine residues on both histone and other proteins by specific “reader” elements is important for chromatin regulation, gene expression, and control of cell-cycle progression. Recently the crucial role of these reader proteins in cancer development and dediffe...

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Autors principals: Herold, J. Martin, Ingerman, Lindsey A, Gao, Cen, Frye, Stephen V
Format: Artigo
Idioma:Inglês
Publicat: Bentham Open 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229088/
https://ncbi.nlm.nih.gov/pubmed/22145013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397301005010051
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