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CHEMICAL GENETIC AND EPIGENETICS: Chemical probes for methyl lysine reader domains

The primary intent of a chemical probe is to establish the relationship between a molecular target, usually a protein whose function is modulated by the probe, and the biological consequences of that modulation. In order to fulfill this purpose, a chemical probe must be profiled for selectivity, mec...

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Detalhes bibliográficos
Publicado no:Curr Opin Chem Biol
Main Authors: James, Lindsey I., Frye, Stephen V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018434/
https://ncbi.nlm.nih.gov/pubmed/27348158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2016.06.004
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