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Getting a handle on chemical probes of chomatin readers

The dynamic nature of histone post-translational modifications such as methylation or acetylation makes possible the alteration of disease associated epigenetic states through the manipulation of the associated epigenetic machinery. One approach is through small molecule perturbation. Chemical probe...

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Detalhes bibliográficos
Publicado no:Future Med Chem
Main Authors: Waybright, Jarod M, James, Lindsey I
Formato: Artigo
Idioma:Inglês
Publicado em: Newlands Press Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025116/
https://ncbi.nlm.nih.gov/pubmed/31920100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2019-0274
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