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p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β(2) Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma
Corticosteroid insensitivity (CI) is a major barrier to treating severe asthma. Despite intensive research, the molecular mechanism of CI remains uncertain. The aim of this study was to determine abnormality in corticosteroid action in severe asthma and to identify the molecular mechanism of the lon...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228526/ https://ncbi.nlm.nih.gov/pubmed/21917909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.071993 |
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