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p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β(2) Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma

Corticosteroid insensitivity (CI) is a major barrier to treating severe asthma. Despite intensive research, the molecular mechanism of CI remains uncertain. The aim of this study was to determine abnormality in corticosteroid action in severe asthma and to identify the molecular mechanism of the lon...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mercado, Nicholas, To, Yasuo, Kobayashi, Yoshiki, Adcock, Ian M., Barnes, Peter J., Ito, Kazuhiro
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Pharmacology and Experimental Therapeutics 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228526/
https://ncbi.nlm.nih.gov/pubmed/21917909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.071993
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