Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation

Lignende værker

• RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
  af: Eto, Tomonori, et al.
  Udgivet: (2003)
• C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
  af: Sabouri, Somayeh, et al.
  Udgivet: (2014)
• A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
  af: Kotani, Ai, et al.
  Udgivet: (2005)
• Characterization of immunoglobulin gene somatic hypermutation in the absence of activation-induced cytidine deaminase
  af: Longo, Nancy S., et al.
  Udgivet: (2008)
• Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
  af: Okazaki, Il-mi, et al.
  Udgivet: (2011)