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The Trojan Horse Liposome Technology for Nonviral Gene Transfer across the Blood-Brain Barrier

The application of blood-borne gene therapy protocols to the brain is limited by the presence of the blood-brain barrier (BBB). Viruses have been extensively used as gene delivery systems. However, their efficacy in brain is limited by the lack of transport across the BBB following intravenous (IV)...

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Detalhes bibliográficos
Main Authors: Boado, Ruben J., Pardridge, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228285/
https://ncbi.nlm.nih.gov/pubmed/22175028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/296151
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