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Drug transport across the blood–brain barrier

The blood–brain barrier (BBB) prevents the brain uptake of most pharmaceuticals. This property arises from the epithelial-like tight junctions within the brain capillary endothelium. The BBB is anatomically and functionally distinct from the blood–cerebrospinal fluid barrier at the choroid plexus. C...

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Detalhes bibliográficos
Autor principal: Pardridge, William M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494002/
https://ncbi.nlm.nih.gov/pubmed/22929442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.126
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