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The Blood-Brain Barrier: Bottleneck in Brain Drug Development

Summary: The blood-brain barrier (BBB) is formed by the brain capillary endothelium and excludes from the brain ∼100% of large-molecule neurotherapeutics and more than 98% of all small-molecule drugs. Despite the importance of the BBB to the neurotherapeutics mission, the BBB receives insufficient a...

詳細記述

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書誌詳細
出版年:NeuroRx
第一著者: Pardridge, William M.
フォーマット: Artigo
言語:Inglês
出版事項: Am. Soc. for Experimental NeuroTherapeutics 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15717053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1602/neurorx.2.1.3
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