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The Blood-Brain Barrier: Bottleneck in Brain Drug Development
Summary: The blood-brain barrier (BBB) is formed by the brain capillary endothelium and excludes from the brain ∼100% of large-molecule neurotherapeutics and more than 98% of all small-molecule drugs. Despite the importance of the BBB to the neurotherapeutics mission, the BBB receives insufficient a...
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| Publicado no: | NeuroRx |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Am. Soc. for Experimental NeuroTherapeutics
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15717053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1602/neurorx.2.1.3 |
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