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Drug transport across the blood–brain barrier
The blood–brain barrier (BBB) prevents the brain uptake of most pharmaceuticals. This property arises from the epithelial-like tight junctions within the brain capillary endothelium. The BBB is anatomically and functionally distinct from the blood–cerebrospinal fluid barrier at the choroid plexus. C...
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| Format: | Artigo |
| Jezik: | Inglês |
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Nature Publishing Group
2012
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494002/ https://ncbi.nlm.nih.gov/pubmed/22929442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.126 |
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