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Cancer and the blood–brain barrier: ‘Trojan horses' for courses?
The blood–brain barrier (BBB) limits the bioavailability of most bioactive molecules and drugs in the CNS, leaving clinicians with only a few options for pharmacotherapy. In this issue Regina et al. demonstrate that a ‘Trojan horse' drug conjugate, acting as a substrate of a physiological BBB r...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538701/ https://ncbi.nlm.nih.gov/pubmed/18587417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.274 |
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