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Blood-brain barrier delivery of protein and non-viral gene therapeutics with molecular Trojan horses
The products of biotechnology, recombinant proteins, monoclonal antibodies, antisense, RNA interference, or non-viral gene transfer, cannot be developed as pharmaceuticals for the brain, unless these molecules are re-formulated to enable transport across the blood-brain barrier (BBB). Large molecule...
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| 主要作者: | |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701689/ https://ncbi.nlm.nih.gov/pubmed/17512078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.04.001 |
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